Nephrology, dialysis and transplantation.
نویسندگان
چکیده
This review highlights some of the more important advances that have been made in renal physiology, nephrology and renal replacement therapy. There have been dramatic advances in our understanding of the molecular mechanisms in physiology, pathology and in the pharmacology ofimmunosuppression. We understand better the factors that lead to the relentless progression to end stage renal failure in conditions where the original or specific disease may well be inactive. Intervention is now possible to slow progression. Long term dialysis has produced its own special problems and increased ingenuity and improved biotechnology are required. The revolution occurring in genetic engineering is paying its dividends to the dialysis populations through the remarkable benefits of human recombinant erythropoietin. The elusive goal of transplantation without infection or rejection remains a distant objective but developments in monoclonal antibody production and the early claims for FK506 are rapidly being put to the test.
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عنوان ژورنال:
- Postgraduate medical journal
دوره 66 777 شماره
صفحات -
تاریخ انتشار 1990